Datasets

Carcinomas of the Major Salivary Glands

Scope

The dataset has been developed for the reporting of primary cancer resection and biopsy specimens of malignancies arising from the major salivary glands (parotid, submandibular and sublingual glands). For resections of recurrent disease, the reporting guide may be used pragmatically although some data elements may be not applicable nor assessable. Melanomas, lymphomas, and sarcomas are dealt with in separate ICCR datasets. Minor salivary gland malignancies arising in the oral cavity, nasal cavity and paranasal sinuses, larynx, hypopharynx, trachea, nasopharynx, oropharynx, gnathic bones, and ear-temporal bone specimens are staged according to their anatomical sub-site and are dealt with in separate ICCR datasets. Minor salivary gland tumours are rare with insufficient quality evidence currently to support a separate dataset, recognising this is a limitation. Further, the ICCR follows Union for International Cancer Control (UICC) guidance for staging, and the major salivary gland system is not applicable to minor salivary glands. The notes on histological typing and grading in this dataset may be used to inform reporting of minor salivary gland malignancies. In addition, neck dissections and nodal excisions are dealt with in a separate dataset, and this dataset should be used in conjunction, where applicable.

This dataset is based on histology, but if cytology is the only material available, we recommend using the ‘other’ box in the operative procedure section to record appropriate information.

For bilateral tumours, a separate dataset should be completed for each tumour.

Publication History

This dataset was developed with the kind support of the North American Society of Head and Neck Pathology (NASHNP), American Academy of Oral and Maxillofacial Pathology (AAOMP), International Association of Oral and Maxillofacial Pathologists (IAOP), and British Society for Oral and Maxillofacial Pathology (BSOMP).

2nd edition – July 2024. Updated following the publication of the 2024 World Health Organization (WHO) Classification of Head and Neck Tumours, 5th edition.

SUMMARY OF CHANGES

• Added a new element ‘Clinical information’.
• Updated the ‘Specimen(s) submitted’ element.
• Updated the ‘Tumour site’ element.
• Added a separate element ‘Tumour laterality’.
• Added a new element ‘Block identification key’.
• Updated the ‘Histological tumour type’ element.
• Updated the ‘Histological tumour grade’ element.
• Updated the ‘Extent of invasion’ element.
• Updated the ‘Coexistent pathology’ element.
• Updated the ‘Ancillary studies’ element.
• Other minor updates to elements were also included.
• Revised all notes, including incorporation of the most recent 2024 WHO Classification.

  • To reference this dataset please use the following citation: Thompson LDR, Bishop JA, Hyrcza MD, Ihrler S, Leivo I, Nagao T, Rupp NJ, Skalova A, Stenman G, Vander Poorten V, van Herpen C, Helliwell T (2024). Carcinomas of the Major Salivary Glands Histopathology Reporting Guide. 2nd edition. International Collaboration on Cancer Reporting; Sydney, Australia. ISBN: 978-1-922324-51-1.

1st edition – September 2018

  • To reference this dataset please use the following citation: Seethala RR, Altemani A, Ferris RL, Fonseca I, Gnepp DR, Ha P, Nagao T, Skalova A, Stenman G, Thompson LDR (2018). Carcinomas of the Major Salivary Glands Histopathology Reporting Guide. 1st edition. International Collaboration on Cancer Reporting; Sydney, Australia. ISBN: 978-1-925687-21-7.
  • Read more on the Carcinomas of the major salivary glands dataset from the journal article written by the dataset authors: Data set for the reporting of carcinomas of the major salivary glands: Explanations and recommendations of the guidelines from the international collaboration on cancer reporting (ICCR). Seethala RR, Altemani A, Ferris RL, Fonseca I, Gnepp DR, Ha P, Nagao T, Skalova A, Stenman G, Thompson LDR. Arch Pathol Lab Med. 2019 May;143(5):578-586. doi: 10.5858/arpa.2018-0422-SA. Epub 2018 Nov 30. ​

Expert Committee

The 2nd edition of the dataset for Carcinomas of the major salivary glands was developed by the following international team:
  • Chair and Series Champion – Lester Thompson, USA
  • ICCR representative – Tim Helliwell, UK
Domain experts:
  • Justin Bishop, USA
  • Martin Hyrcza, Canada
  • Stefan Ihrler, Germany
  • Ilmo Leivo, Finland
  • Toshitaka Nagao, Japan
  • Niels Rupp, Switzerland
  • Alena Skalova, Czech Republic
  • Göran Stenman, Sweden
  • Vincent Vander Poorten, Belgium
  • Carla van Herpen, The Netherlands

Authors of the previous edition of this dataset are available here.

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