The International Collaboration on Cancer Reporting (ICCR) is planning to develop a dataset(s) for gastrointestinal neuroendocrine tumours (NETs), which are generally staged separately to other gastrointestinal tumours.
Therefore, neuroendocrine carcinomas (NECs) but not NETs are included in the scope of the following Digestive tract datasets: Colorectal cancer; Carcinoma of the stomach; Endoscopic resection of the stomach; Carcinoma of the oesophagus; and Endoscopic resection of the oesophagus and oesophagogastric junction.
Colorectal excisional biopsies (polypectomies) are commonly used as a screening tool and many NETs are diagnosed in these specimens. Therefore, the Colorectal excisional biopsy (polypectomy) dataset can be used to report all neuroendocrine neoplasms found in these specimens.
The Carcinoma of the exocrine pancreas & Intrahepatic cholangiocarcinoma, perihilar cholangiocarcinoma and hepatocellular carcinoma datasets have not included NECs within the dataset scope, due to the complex idiosyncrasies and limited evidentiary data on these lesions. The inclusion of NECs in these datasets will be revisited at the time of the next scheduled update.
Until such time, please refer to the Royal College of Pathologists UK (RCPath UK) and the College of American Pathologists (CAP) NET protocols: