Renal Biopsy for Tumours

2nd edition – May 2025

Updated following the publication of the 2022 World Health Organization (WHO) Classification of Urinary and Male Genital Tumours, 5th edition.

This 2nd edition dataset was developed with the kind support of the International Society of Urological Pathology (ISUP).

SUMMARY OF CHANGES

• Revised guide to harmonise with ICCR style for element titles and value list.
• Revised scope for clarity and to harmonise with ICCR style.
• Revised ‘Operative procedure’ element.
• Revised ‘Specimen laterality’ element.
• Added a new element ‘Block identification key’.
• Renamed ‘Histological tumour grade’ to ‘Provisional histological tumour grade’.
• Renamed ‘Sarcomatoid morphology’ to ‘Sarcomatoid features’.
• Renamed ‘Rhabdoid morphology’ to ‘Rhabdoid features’.
• Renamed ‘Co-existing pathology in non-neoplastic kidney’ to ‘Coexisting non-neoplastic kidney’ and update the value listing.
• Updated the ‘Ancillary studies’ element, including adding in ‘Representative blocks for ancillary studies’.
• Other minor updates to elements were also included.
• Revised all notes, including incorporation of the 2022 World Health Organization Classification of Urinary and Male Genital Tumours, 5th edition.

• To reference this dataset please use the following citation: Moch H, Williamson S, Browning L, Brunelli M, Gorban G, Hirsch M, Lopez-Beltran A, Mohanty SK, Ohashi R, Rogers C, Saleeb RM, Schmidinger M, Verkarre V, Srigley JR (2025). Renal Biopsy for Tumour Histopathology Reporting Guide. 2nd edition. International Collaboration on Cancer Reporting; Sydney, Australia. ISBN: 978-1-922324-61-0.

1st edition – July 2017

• To reference this dataset please use the following citation: Delahunt B, Srigley JR, Amin MB, Billis A, Camparo P, Evans AJ,  Fleming S, Griffiths D, Lopez-Beltran A, Martignoni G, Moch H, Nacey JN, Zhou M (2017). Renal Biopsy for Tumour Histopathology Reporting Guide. 1st edition. International Collaboration on Cancer Reporting; Sydney, Australia. ISBN: 978-1-925687-01-9.

• Read more on the Carcinoma of renal tubular origin dataset from the journal article written by the dataset authors: Dataset for the reporting of renal biopsy for tumour: recommendations from the International Collaboration on Cancer Reporting (ICCR). Delahunt B, Srigley JR, Judge M, Amin M, Billis A, Camparo P, Fleming S, Griffiths D, Lopez-Beltran A, Martignoni G, Moch H, Nacey JN, Zhou M, Evans AJ. J Clin Pathol. 2019 Sep;72(9):573-578. doi: 10.1136/jclinpath-2019-205959. Epub 2019 Jul 12.

The 2nd edition of the dataset for Renal biopsy for tumour was developed by the following international team:

• Co-chair – Holger Moch, Switzerland
• Co-chair – Sean Williamson, USA
• Series Champion and ICCR representative – John R Srigley, Canada

Domain experts

• Lisa Browning, UK
• Matteo Brunelli, Italy
• Nina Gorban, Russia
• Michelle Hirsch, USA
• Antonio Lopez-Beltran, Portugal
• Sambit Mohanty, India
• Riuko Ohash, Japan
• Craig Rogers, USA
• Rola Saleeb, Canada
• Manuela Schmidinger, Austria
• Virginie Verkarre, France

Authors of previous edition of this dataset are available here.