This dataset has been developed for excision specimens of the kidney for neoplasms of renal tubular origin. Urothelial carcinoma arising from the upper renal tract, Wilms tumours and other nephroblastic and mesenchymal tumours are not included. Metastatic tumours are excluded from this dataset. This dataset is not to be used for clearly benign tumours, such as papillary adenoma and oncocytoma. However other neoplasms of uncertain behaviour (e.g., clear cell papillary tumours, other oncocytic tumours) may be reported using this dataset.
Biopsy specimens are not included – a separate ICCR dataset is available and should be used for these cases.
This dataset is designed for the reporting of a single laterality of specimen i.e., left or right. If both lateralities are submitted then separate datasets should be completed.
2nd edition – May 2025
Updated following the publication of the 2022 World Health Organization (WHO) Classification of Urinary and Male Genital Tumours, 5th edition.
This 2nd edition dataset was developed with the kind support of the International Society of Urological Pathology (ISUP).
SUMMARY OF CHANGES
• Renamed title of guide to ‘Renal epithelial neoplasms’.
• Revised guide to harmonise with ICCR style for element titles and value list.
• Revised scope for clarity and to harmonise with ICCR style.
• Added a new element ‘Block identification key’.
• Renamed ‘Sarcomatoid morphology’ to ‘Sarcomatoid features’.
• Renamed ‘Rhabdoid morphology’ to ‘Rhabdoid features’.
• Updated the ‘Necrosis’ element.
• Updated the ‘Extent of invasion’ element.
• Renamed ‘Lymphovascular invasion’ to ‘Lymphovascular invasion in adjacent kidney’.
• Updated the ‘Ancillary studies’ element, including adding ‘Representative blocks for ancillary studies’.
• Updated the ‘Pathological staging’ element to UICC TNM8 staging.
• Other minor updates to elements were also included.
• Revised all notes, including incorporation of the 2022 World Health Organization Classification of Urinary and Male Genital Tumours, 5th edition.
Minor update to the 1st edition – Version 1.1 July 2018
1st edition – July 2017
The 2nd edition of the dataset for Renal epithelial neoplasms was developed by the following international team:
Domain experts:
Authors of previous edition of this dataset are available here.