Datasets
2nd edition – November 2025
Updated following the publication of the 2025 World Health Organization (WHO) Classification of Endocrine and Neuroendocrine Tumours, 5th edition.
SUMMARY OF CHANGES
• Updated to Union for International Cancer Control TNM9 staging, including errata published October 2025.
• Revised guide to harmonise with ICCR style for element titles and value list.
• Revised scope for clarity and to harmonise with ICCR style.
• Updated the ‘Clinical information’ element.
• ‘Pre-operative biochemical information’ was changed to a core element (apart from the ‘other’ category which remained non-core).
• ‘Operative findings’ was changed to a core element (apart from the ‘other’ category which remained non-core) and ‘cystic’ was added.
• Added a new non-core element ‘Specimen dimensions’.
• Added a new non-core element ‘Block identification key’.
• Updated the ‘Mitotic count’ element.
• Renamed the ‘Necrosis’ element ‘Tumour necrosis’.
• Removed the element ‘Histological tumour grade’.
• Updated the ‘Extent of invasion’ element.
• Renamed the ‘Lymphovascular invasion’ element to make two new elements ‘Lymphatic invasion’ and ‘Vascular invasion’.
• Updated the ‘Margin status’ element.
• Updated the ‘Ancillary studies’ element, including changing ‘Ki-67 proliferation index’ to core and adding ‘Representative blocks for ancillary studies’ as non-core.
• Other minor updates to elements were also included.
• Revised all notes, including incorporation of the 5th edition WHO Classification of Endocrine and Neuroendocrine Tumours.
1st edition – December 2019
Authors of the previous edition of this dataset are available here.
