The following figure reflects both the organisational structure of the ICCR and the process flow of dataset development.
Board of Directors
The ICCR Board of Directors comprises representatives from the 5 foundation partners:
European Society of Pathology (ESP), the Royal College of Pathologists UK (RCPath), the College of American Pathologists (CAP), the Royal College of Pathologists of Australasia (RCPA) and the Canadian Association of Pathologists (CAP-ACP) in association with the Canadian Partnership Against Cancer (CPAC). As well as representatives from the American Society of Clinical Pathology (ASCP) and Royal College of Physicians of Ireland (RCPI), Faculty of Pathology.
John R Srigley
Dr John R Srigley, MD, FRCPC, FRCPath, FRCPA [Hon.]
Consultant in Oncological and Urological Pathology.
Dr Srigley is a graduate of the Faculty of Medicine, University of Toronto. Following oncological pathology training at the University of Toronto and MD Anderson Cancer Centre in Houston, Dr Srigley was Director of Surgical Pathology at Sunnybrook Health Science Center and Chief of Laboratory Medicine at the Credit Valley Hospital. Currently he is the Chief and Medical Director of the Program of Laboratory Medicine and Genetics at Trillium Health Partners, one of the largest community-academic hospitals in Canada and also a Professor in the Department of Pathology and Molecular Medicine at McMaster University. Dr Srigley is an international consultant and educator in the fields of oncological and urological pathology and has contributed extensively to the literature. He is an editor/author of three textbooks on urological pathology including the series 3 AFIP Fascicle on Tumors of the Prostate Gland. Dr Srigley has been an author and member of the international working groups for the 2004 and 2016 WHO Blue Books on Tumors of the Urinary System and Male Genital Organs. His research interests include clinical-pathological and translational studies of urological cancer, population-level quality initiatives in cancer pathology and the role of the pathologist in cancer control. Dr Srigley is a Past President of the International Society of Urological Pathologists (ISUP) and the Ontario Association of Pathologists.
Dr Srigley is the Expert Lead for Pathology and Chair of the National Pathology Standards Committee at the Canadian Partnership Against Cancer (CPAC) and represents Canada on the American Joint Committee on Cancer (AJCC). Dr Srigley has championed the role of Pathologist as Diagnostic Oncologist and is a strong advocate for population-level standardized synoptic pathology reporting. Dr Srigley was the inaugural Head of Pathology and Laboratory Medicine at Cancer Care Ontario (2004-2013) and led the clinical implementation of discrete data field synoptic pathology reporting in Ontario. Working with the National Pathology Standards Committee and the Canadian Association of Pathologists, Dr Srigley was a key leader in securing formal endorsement of the College of American Pathologists(CAP) cancer checklists as pan-Canadian content standards for cancer pathology reporting. He is also a founding board member of the International Collaboration on Cancer Reporting (ICCR) and has provided advice on population-level standardized cancer reporting to CAP, the RCPA Structured Cancer Pathology Reporting Project in Australiasia as well as groups in Poland, Norway and Brazil.
Professor Tim Helliwell, MD, MB, BChir, FRCPath, graduated in medicine at the University of Cambridge and undertook his training in histopathology in the university Department of Pathology in Liverpool. Since 1984 has been a Consultant Histopathologist at the Royal Liverpool University Hospital (appointed in 1984) and is currently Clinical Director for Cellular Pathology in Liverpool Clinical Laboratories and Honorary Professor of Pathology, University of Liverpool.
As a Consultant Histopathologist in Liverpool for 31 years, Professor Helliwell has a wide experience in diagnostic work. In 1997 the Department introduced specialist reporting and since then he has been lead histopathologist for head and neck, thyroid, bone, soft tissue and skeletal muscle pathology. Professor Helliwell participates in External Quality Assurance Schemes for orthopaedic (soft tissue and bone) and head and neck pathology and he regularly undertakes undergraduate and post-graduate teachings in these areas.
Professor Helliwell MD thesis involved studies of techniques to demonstrate damage to skeletal muscle. He is an author or co-author of over 126 publications, and has contributed to chapters of the current revision of the WHO Classification of Tumours of the Head and Neck. Ongoing research interests are in the molecular pathology of head and neck cancer and soft tissue sarcomas, and in evidence-based pathology, particularly for head and neck cancer.
Professor Helliwell is the lead author for the national pathology guidelines for head and neck cancer published by the Royal College of Pathologists, and was a member of the NICE editorial board for the Improving Outcomes Guidance for Head and Neck Cancer. He was Chair of the Merseyside and Cheshire Pathology Cancer Network Group (2004-7), and helped to shape the development of cancer pathology dataseets as Chair of the Cancer Services Working Group of the Royal College of Pathologists (2005-9). Professor Helliwell was sub-specialty adviser in ENT Pathology (2008-2012) to the Royal College of Pathologists and lead pathologist on the head and neck cancer site specific group of the National Cancer Intelligence Network and lead pathologist for review of national cancer dataset (2009-2012). He was an elected member of Council of the Royal College of Pathologists (2012-2014), leading on quality and performance indicators, and in November 2014 was elected as Vice President of the Royal College of Pathologists with responsibilities for training, assessments, examinations and research.
Executive Officer (Immediate past president)
Dr David Ellis, MBBS, FRCPA, is a graduate of the University of Melbourne and trained as an anatomical pathologist at Royal Prince Alfred Hospital, Sydney, NSW. He has a particular interest in haematopathology and established the Victorian Lymphoma Registry in 1992, later to become co-Chair of the Australian Cancer Network Guidelines for the Diagnosis and Management of Lymphoma. He chaired the National Structured Pathology Reporting Project in Australia for 6 years from its inception in 2009, initially as chair of the RCPA Anatomical Pathology Advisory Committee, and subsequently as founding Chair of the RCPA Cancer Services Advisory Committee (CanSAC). In 2011, Dr Ellis was appointed as inbound liaison to the Cancer Committee of the College of American Pathologists (CAP). He is Vice President of the Australasian Division of the International Academy of Pathology and a member of the IAP International Executive Committee. Since 2014 he has represented the ICCR on the UICC TNM Staging Committee in Geneva.
He currently holds an associate professorship at Flinders University, and is CEO of Clinpath Laboratories, South Australia.
Dr Thomas Wheeler, MD, is board certified in Anatomic Pathology, Clinical Pathology, and Cytopathology and has served over 35 years in academic, consultative, and director/clinical roles with leading University medical centers and healthcare enterprises.
Dr Wheeler received his medical degree with high honors from Baylor College of Medicine in Houston, Texas, in 1977. At Baylor College of Medicine and Affiliated Hospitals, he completed his residency in Anatomic and Clinical Pathology functioning as Chief Resident in Pathology. For over 29 years, Dr Wheeler has served on the faculty at Baylor in the Departments of Pathology and Urology; he was appointed Associate Chairman of Pathology in 1995, Professor of Pathology and Urology in 2001. He presently serves as the W.L. Moody, Jr. Professor of Pathology (appointed in 2013), and Chair of the Department of Pathology & Immunology (appointed in 2007).
Dr Wheeler is a dedicated and outstanding teacher of residents and medical students serving for many years as a lecturer in the second year Pathology Medical School Course at Baylor College of Medicine and as Attending Pathologist at Ben Taub General Hospital.
Along with his many faculty roles, Dr Wheeler‘s expertise in pathology, particularly genitourinary pathology, is reflected in his membership on Editorial Boards for Human Pathology, Prostate, American Journal of Surgical Pathology, and Archives of Pathology and Laboratory Medicine. He is also Editor-in-Chief of eMedicine’s online textbook of Pathology and Laboratory Medicine and writes a monthly Pathology and Laboratory Medicine blog for Medscape and is an active member of their Editorial Board.
Dr Wheeler is an avid clinical researcher with special interests in studies related to diagnosis and prognosis in prostate cancer- his research has anchored the Pathology Department’s role in Baylor College of Medicine’s highly acclaimed prostate cancer program for many years. Since 1992, he has been involved on major research grants totaling over $750,000 including his involvement as the Director of the Pathology Core for Baylor College of Medicine’s Prostate SPORE grant.
Dr Wheeler has participated on numerous advisory boards and committees for both academic and industry related institutions. He is a well known author and lecturer with over 280 publications and 60 speaker invitations. He has also served as a participant, committee member, and/or officer to a large number of national groups, programs and societies, including the College of American Pathologists, US and Canadian Academy of Pathology, and the Texas Society of Pathologists.
James L Wisecarver
James L Wisecarver, MD, PhD, FASCP
Medical Director, Nebraska Medical Center
Omaha, Nebraska, USA
Dr James L Wisecarver, MD, PhD, FASCP, received his doctor of medicine degree from the University of Nebraska Medical Center (UNMC), Omaha, Neb. Dr Wisecarver earned a bachelor’s degree in biology from Doane College, Crete, Neb., and a doctorate degree in physiology from Creighton University, Omaha. He completed a residency in combined anatomic and clinical pathology at the University of Nebraska Medical Center and then joined the faculty in the Department of Pathology/Microbiology at UNMC as an Assistant Professor in 1990. He was promoted to Associate Professor in 1995 and to Professor in 2002. Currently, he serves as Vice Chair for Clinical Affairs and as Medical Director for the Clinical Laboratories at The Nebraska Medicine. He also serves as the Director of the Human DNA Identification Laboratory at UNMC.
Dr Wisecarver is currently President-elect of the American Society for Clinical Pathology (ASCP) Board of Directors. "My involvement in ASCP activities dates back to the Council on Continuing Education (CCE) when I became active with the section on diagnostic immunology and molecular pathology. Later, I was elected to the Board of Governors of the ASCP Board of Registry (now Board of Certification). While serving on the Board, I helped organize a new examination committee to develop the molecular biology examination and associated credential that is now being offered through the ASCP Board of Certification." Dr. Wisecarver has also been a member of the ASCP Commission on Science, Technology and Public Policy, the Fellow Council, and the Pathologists Workforce Task Force. He has also chaired the Awards Committee.
Dr Wisecarver has organized and presented molecular diagnostics workshops offered both through ASCP and the United States and Canada Academy of Pathology (USCAP).
Recently, Dr Wisecarver celebrated 44 years of marriage with his wife, Patty. They have two grown children and four grandchildren. He enjoys spending time with the grandchildren, along with golfing, fishing and hunting.
Professor Kieran Sheahan, MB, BCh, BAO, BSc, FRCPI, FFPath, FCAP, FFRCPath, is a Consultant Histopathologist at St. Vincent's University Hospital (SVUH), Dublin & is Clinical Professor at University College Dublin School of Medicine. He trained at the Mallory Institute of Pathology, Boston, where he was Assistant Professor of Pathology at Boston University Medical School.
Professor Sheahan took up his present appointment in 1992, became Associate Clinical Professor, UCD School of Medicine in 2007 & Full Clinical Professor in 2014. He is also a Director of the Centre for Colorectal Disease, SVUH. He is the Chair of the Histopathology steering committee for the Irish National ‘BowelScreen’ programme & is on the Working Committee of the National Histopathology Quality Improvement Programme of the Faculty of Pathology. He is also Director of Education & Training in the Faculty of Pathology, RCPI. Professor Sheahan was the founding Treasurer of the Irish Society of Surgical Pathology (ISSP) & former President of the ISSP. He was on the Board of the Irish Cancer Registry from 1997 to 2002.
Professor Sheahan research interests include prognostic & predictive markers in colorectal cancer, familial gastrointestinal cancer, & application of immunohistochemical & molecular genetic techniques in pathology. Professor Sheahan has numerous collaborations internationally, especially in the field of colorectal cancer. He is author of over 140 original publications in peer-reviewed biomedical journals, & has authored numerous reviews & book chapters. He is co-editor of the upcoming Morson & Dawson’s Gastrointestinal Pathology (6th edition).
Professor James Kench, MB BS, BSc(Med), FRCPA, graduated in medicine at the University of Sydney in 1986. He commenced training in anatomical pathology in 1988 at Westmead Hospital then completed his training at Prince of Wales Hospital, Sydney NSW, before being awarded his Fellowship of the Royal College of Pathologists of Australasia in 1993. He is also a member of the International Academy of Cytology and International Fellow of the College of American Pathologists.
After working as a staff specialist at St Vincent’s and Westmead Hospitals, in 2009 Professor Kench became Head of Tissue Pathology and Diagnostic Oncology (formerly Anatomical Pathology) at Royal Prince Alfred Hospital in Sydney, where he is currently also Local Pathology Director-RPA. He was appointed as a Clinical Professor at University of Sydney in 2009 and has subspecialty expertise in prostatic, pancreatic and hepatic pathology. Professor Kench is an International Councillor of the International Society of Urological Pathology (ISUP), as well as being a member of the Australian Upper Gastro-intestinal Cancer Registry Steering Committee and the Hepatobiliary Subcommittee, the Australian and New Zealand Urogenital and Prostate Cancer Trials Group (ANZUP) Scientific Advisory Committee, and the NSW Cancer Council Prostate and Colorectal Cancer Expert Advisory Panels.
Professor Kench has published over 160 peer reviewed journal articles plus several books and book chapters. He has a longstanding research collaboration with the Prostate Cancer Group at the Garvan Institute of Medical Research and is an Executive member of the Australian Prostate Cancer Research Centre-NSW. He has been actively involved in structured reporting initiatives since 2008 including as Chair of the National Structured Pathology Reporting Project for 4 years from 2014, and as a member of the ICCR Dataset Steering Committee for 4 years.
Dr Yan-hui Liu, MD, is Director of the Department of Pathology and Laboratory Medicine at Guangdong Provincial People’s Hospital, Guangzhou, China. She is the Chairman-in-waiting of the Oncology Pathology Committee of the Chinese Anti-cancer Association and also Medical laboratory ISO15189 reviewer at China National Accreditation Council for Conformity Assessment (CNAS).
After Xiangya Medical College at Zhongnan University, Dr Liu had worked as a Pathologist at the Cancer Hospital of Chinese Academy of Medical Sciences, Beijing from 1983 to 1993. She had served as Director of Department of Pathology from 1992 to 1993.
Since 2003, Dr Liu is nominated as Consultant Pathologist and Director of the Department of Pathology and Laboratory Medicine at Guangdong Provincial People’s Hospital, Guangzhou. She specializes in Hemato-pathology, especially the diagnosis and study of lymphoma. She served also as Central Pathologist for national clinical trials in lung and breast cancer fields.
Professor Peter Schirmacher is Director of the Institute of Pathology (IPH) of Heidelberg University (Germany) since 2004, Chairman of the German Society of Pathology and Council Member of the European Association of Pathology, Board member of the National Center of Tumor Diseases, member of the German Academy of Sciences Leopoldina, honorary member of the Hungarian Academy of Sciences, and Principle Investigator in many national and international consortia.
Professor Schirmacher studied Medicine at Mainz University (Germany) and Molecular Biology at Albert Einstein College, New York, received training and board certification in Pathology and Molecular Pathology at Mainz University and was Professor of Pathology at Cologne University from 1998 until 2004.
Professor Schirmacher scientific interest centers on liver and molecular pathology with specific emphasis on molecular pathogenesis of hepatobiliary cancer; he has contributed to over 600 publications and numerous guidelines mainly centering on these topics. Professor Schirmacher is coordinator of the Coordinative Research Center ‘Liver Cancer’ of the German Research Foundation involving three University Centers and about 50 Researchers. IPH is Center of Excellence of the ESP for Liver and Molecular Pathology.
Katia Ramos Moreira Leite
Dr Katia Ramos Moreira Leite, MD, PhD is Associated Professor and Chairman of the Laboratory of Medical Investigation of the University of Sao Paulo Medical School in Sao Paulo, Brazil. Works at the Sirio Libanes Hospital in Sao Paulo, Brazil since 1988, being responsible for the uropathology and liver transplant pathology.
Dr Leite is Vice-President since 2016 and President-Elected of the Brazilian Society of Pathology for the term 2020-2022. Councilor for South America of the International Society of Urological Pathology (ISUP) from 2015 to 2019.
Associate Editor of the journal Surgical and Experimental Pathology. Member of the Editorial Board of Pathology Journal, Journal of Carcinogenesis and International Brazilian Journal of Urology.
Dr Leite has 460 publications in peer reviewed journal articles plus several book chapters.
Annie Nga-Yin Cheung
Professor Cheung is Laurence L T Hou Professorship in Anatomical Molecular Pathology and Clinical Professor at the Department of Pathology, The University of Hong Kong (HKU). She is the key pathologist for gynecological histopathology and cytology in Queen Mary Hospital, Director of the HKU Cervical Cytology Laboratory and the University Pathology Laboratory (Molecular Pathology) as well as the Chief of Service of Pathology, HKU-Shenzhen Hospital.
Professor Cheung was a HKU MBBS graduate and continued her studies at HKU for her MD and PhD. She received her postgraduate gynecological pathology training in the University of Manchester, UK, Massachusetts General Hospital, Harvard Medical School and The Armed Forces Institute of Pathology, USA. Professor Cheung’s research focuses on ovarian, endometrial and cervical cancers as well as gestational trophoblastic disease, aiming at investigating diagnostic and prognostic markers as well as molecular targets for better therapy. Professor Cheung has received awards on education and research. She has over 250 publications and has contributed to chapters in the WHO Classification of Tumours of Female Reproductive Organs.
Professor Cheung is currently Standing Member, Editorial Board of 5th Edition WHO Classification of Tumours, Commissioner, Lancet Commission on Diagnostics and Chairman, Credentials and Appeals Committee, The Hong Kong College of Pathologists. She is also the Advisor to Executive Board, Asian Oceania Research on Genital Infections and Neoplasia and Immediate Ex-President of The Hong Kong College of Pathologists. Professor Cheung has been President of Hong Kong Society for Colposcopy and Cervical Pathology as well as Council Member of the International Federation for Cervical Pathology and Colposcopy and Council Member at Large of the International Society of Gynaecological Pathologists.
Professor Gerald Hoefler is Professor for Pathology and Director of the Diagnostic and Research Institute of Pathology of the Medical University of Graz (Austria) since 2008. He was President of the Austrian Society of Pathology (ÖGPath) 2016-18 and is currently Chairman of the Working Group for Molecular Pathology, European Society for Pathology (ESP).
Professor Hoefler was a Board Member on the Austrian Science Foundation (FWF) 2007-14 and is a member of the Senate of the Medical University of Graz since 2009. He is the Director of the FWF funded Doctoral College Metabolic and Cardiovascular Disease since 2010.
Professor Hoefler studied Medicine at the Karl-Franzens-University Graz (Austria). He received an Erwin-Schrödinger fellowship of the Austrian Science Foundation (FWF), which he spent at the Kennedy Institute for Handicapped Children, Johns Hopkins School of Medicine, Baltimore, MD, USA (1986-88) and an Otto Loewi fellowship which he spent at the Department of Medical Biochemistry, University of Graz (1989-90). Professor Hoefler received training and board certification (1995) in Laboratory Medicine and in Pathology and Genetics (1997) at the Karl-Franzens-University Graz.
His particular scientific interest focuses on molecular pathology, neoplasia and lipid metabolism. Recently, his research group investigates the effects of tumour growth on triglyceride metabolism. During the last five years Professor Hoefler has been awarded over 4 Mio. € in competitive 3rd party funding. He has published 238 papers listed in SCI/SSCI and/or PUBMED with a combined IF of 1166 that have been cited >9100 times. His current H-index is 53.
Professor Cohen is Honorary Professor (Oncology and Metabolism) at the University of Sheffield, South Yorkshire, UK.
*Note it is a requirement of Australian law that companies incorporating in Australia have 2 Australian resident directors.
Professor Sanchia Aranda was appointed CEO of Cancer Council Australia in August 2015.
Professor Aranda has more than 30 years’ experience in cancer control as a clinician, researcher, educator and senior healthcare administrator.
From her early career as a Registered Nurse in New Zealand she specialised in cancer and palliative care, completing a Bachelor of Applied Science, a Master of Nursing and a doctoral thesis exploring nurse-patient relationships in cancer and palliative care. Her most recent role was Director of Cancer Services and Information and Deputy CEO at the Cancer Institute NSW.
Professor Aranda is President-elect of the Union for International Cancer Control (the world’s peak member-based cancer organisation) and a former President of the International Society of Nurses in Cancer Care.
As well as being a research fellow at the Peter MacCallum Cancer Centre, she holds academic appointments within the School of Health Sciences, University of Melbourne, and the Faculty of Nursing, University of Sydney.
From a digital technology perspective in her research work Professor Aranda has led studies utilising web and application based programs for support of patients, most recently a randomised trial of a remote symptom assessment system with real time health system connectivity. In her previous role at the Cancer Institute NSW she oversaw the development of technology initiatives in cancer registries including automation of data extracts from clinical information systems into the Central Cancer Registry in NSW. She has also been involved in initiatives to routinely collect patient reported outcomes into clinical information systems. In her CINSW role she established clinical data governance functions and ethical approvals for linked datasets.
In August 2015 she took up the role of CEO of Australia’s peak non-government cancer control organisation. In this role she is a strong independent voice on evidence-based cancer control. She is engaged in all fields of cancer from primary prevention through to survivorship and advanced care, and has a particular professional interest in improved ways to care for and support cancer patients and enhanced use of administrative datasets to understand clinical variation and to improve our cancer system.
She is a regular commentator on cancer issues in Australia media.
Professor Aranda’s role in cancer control has been recognised nationally and internationally, and in 2013 she was named the 4th Peter MacCallum Cancer Centre Distinguished Fellow for her contributions to cancer nursing. In 2016 she received the International Society of Nurses in Cancer Care’s Distinguish Merit Award for her contributions to cancer nursing.
Additional directors may be added to the Board of Directors either by becoming sustaining (financially supporting) members or by vote from the general membership (maximum 2 places).
The ICCR Board has strategic oversight of all ICCR operations and financial and legal responsibility for the running of the ICCR and is governed by a charter.
Dataset Steering Committee (DSC)
The ICCR DSC has responsibility for all activities relating to the development of ICCR cancer datasets. Membership is as follows:
- Tim Helliwell - Chair
- John R Srigley
- David Ellis
- Thomas Wheeler
- James Kench
- Kieran Sheahan
- Peter Schirmacher
- Annie Nga-Yin Cheung
- Marta Cohen
Sustaining member representatives
- Joseph D Khoury, CAP, USA
- Michael Eden, RCPath, UK
- Paul Barrett, RCPath, UK
- Iris Nagtegaal, ESP
- Alexandra (Ali) Brown, ASCP
- Ann Treacy, RCPI, Faculty of Pathology
- Chris Hemmings, RCPA
- Blake Gilks, CAP-ACP/CPAC
- Yuan Li, CACA, Committee of Oncopathology
- Fabio Tavora, SBP
- Siu-ming Mak, HKCP
- Sigurd Lax, ÖGPath/IAP Austria
Strategic partner organisation representatives
- Ian Cree, International Agency for Research on Cancer (IARC)
- Ariana Znaor, International Association of Cancer Registries (IACR)
- Marion Pineros, International Association of Cancer Registries (IACR)
- Trishe Leong, IAP-Australasian Division, Australia
- Thomas Gevaert, EORTC
- Pieter Demetter, EORTC
- John R Srigley - Genitourinary Dataset series
- Lester Thompson - Head and Neck Dataset series
- Anthony Gill - Endocrine Dataset series
- Puay Hoon Tan - Breast Dataset series
- Kay Washington - Hepatobiliary Dataset series
- Iris Nagtegaal - Gastrointestinal Tube Dataset series
Project management support
- Tina Selinger, RCPA
- Meagan Judge, ICCR
- Fleur Webster, ICCR
- Gina Green, ICCR
- Doug Murphy, CAP
The Terms of Reference for the ICCR Dataset Steering Committee are available for review.
- George Birdsong, PERT, CAP
- Brian Rous, RCPath
- Samantha Spencer, CAP
- W. Scott Campbell, UNMC
- James Campbell, UNMC
Editorial/Quality Committee (EQ)
The purpose of the ICCR EQ is to provide an independent review of each ICCR dataset prior to public consultation to ensure it adheres to ICCR standards. Currently this committee’s function is undertaken by the DSC.
The Terms of Reference for the planned ICCR EQ Committee are available for review.
Dataset Authoring CommitteeS (DAC)
The ICCR DSC, having selected a specific cancer dataset for development, will invite an appropriately qualified pathologist to take on the role of Chair and a Dataset Authoring Committee (DAC) will then be convened.
DAC’s are convened as needed for the development of specific datasets. They are composed of 8-10 domain specialists, comprising expert pathologists and clinicians. Domain specialists are selected for their expertise in the cancer field and their support of structured pathology reporting of cancer. Geographical and linguistic diversity is sought where possible.